喝咖啡与不喝咖啡,身体三个差距很明显!健康喝咖啡记住这几点There are three distinct differences between those who drink coffee and those who don't! Remember these points for healthy coffee consumption

2024-12-26 09:00:16 admin 3455
咖啡,许多人把它当作提神醒脑、预防困倦的“利器”,甚至有些人每天都要喝2-3杯咖啡。此前已多项研究都证实,喝咖啡确实可带来不少健康益处。
与从不喝咖啡的人相比,这些长期喝咖啡的人身体上会不会有什么变化?日前哈佛大学的一项研究发现:咖啡对肠道影响实在是太大了。
图片关键词
健康时报任璇 摄
经常喝咖啡的人,肠道菌群大变样!
2024年11月,哈佛大学的研究人员在《自然·微生物学》期刊上发表的一项数万人研究发现:经常喝咖啡能改变肠道菌群。与从不喝咖啡的人(每月不足三杯)相比,每天喝三杯咖啡的人,其肠道中有益菌(L.asaccharolyticus)的水平高出4.5-8倍!
图片关键词
研究截图
这项研究是迄今为止,最大规模的人类肠道菌群与咖啡消费之间关联的研究。研究人员将超过2.2万名参与者,根据他们喝咖啡的摄入量分为了3组:
第一组:从不喝咖啡(每月不到3杯)第二组:大量喝咖啡(每天超过3杯)第三组:适度喝咖啡(介于从不喝和大量喝之间)
研究发现,喝咖啡摄入量和人类肠道菌群之间具有密切的联系,在150多种食物中,咖啡与人类肠道菌群的关联性最强。
与从未喝咖啡的人群相比,大量喝咖啡的人群中有益菌(L.asaccharolyticus)的水平高出4.5-8倍。适度喝咖啡的人群中有益菌(L.asaccharolyticus)的水平高出3.4-6.4倍,并且这种差异对全球所有人群来说都是一致的。
图片关键词
咖啡豆,健康时报曹子豪 摄
长期喝咖啡与从不喝咖啡的人,三个方面差距很明显
1. 肠道菌群或有较大差距
正如上述研究中指出的,咖啡对L.asaccharolyticus的水平有显著提升作用,尤其在不喝咖啡和饮用咖啡者之间差异最为明显。①
经常喝咖啡的人,L.asaccharolyticus这种肠道有益菌水平更高。L.asaccharolyticus是一种肠道有益菌,它能帮助肠道产生丁酸,有助于维持肠道屏障功能,帮助预防肠炎和肠癌。
2. 面部皮肤衰老的风险低
2024年,北京协和医学院的研究人员发表在《美容皮肤病学杂志》上的一项研究发现:经常喝咖啡的人能够有效降低面部皮肤衰老的风险。
图片关键词
研究截图
研究综合分析了喝茶、喝咖啡、喝酒精饮料、喝含糖饮料这4种饮品的饮用和面部皮肤老化之间的因果关系。研究发现,在4种饮料中,只有咖啡能够有效降低面部皮肤衰老的风险,咖啡摄入可以降低15%的面部衰老概率。其余3种饮料均未显示出与面部皮肤衰老之间明确的关联。②
换句话说,经常饮用咖啡的人其面部皮肤衰老的风险更低、看起来会更年轻。2014年《国际皮肤病学杂志》上也发表过一项类似研究发现:咖啡的摄入,可以有效保护人类皮肤免受光老化,并减少色素斑沉着。研究人员推测,咖啡美容的原因在于其中含有的绿原酸等多酚物质。③
3. 患心血管病的风险更低
2022年《欧洲预防心脏病学杂志》上的一项研究发现:每天饮用0.5~3杯咖啡,与全因死亡率下降12%,心血管病死亡率下降17%。④
研究指出,咖啡中含有多种生物活性成分,如咖啡因、多酚类化合物等。咖啡因可以刺激中枢神经系统,提高警觉性和注意力,同时还可能对新陈代谢产生一定的促进作用。
而多酚类化合物则具有抗氧化、抗炎等功效,有助于保护身体的细胞免受自由基的损伤,进而维护身体各个器官的正常功能,尤其是心血管系统。
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健康时报图
健康喝咖啡,记住这5点
1. 咖啡不要喝得太烫
无论是咖啡还是喝其他热饮,都不要喝得太烫。2016年国际癌症研究机构(IARC)公布对于咖啡等过热饮品的致癌性评估结果,温度超过65℃等过烫饮品被列入2A类致癌物。即对人致癌性证据有限,但很可能致癌。
2. 每天最好别超5杯
喝咖啡建议每天别超过5杯,2018年中国疾病预防控制中心营养与健康所等联合发布的《咖啡与健康的相关科学共识》建议:健康成人,每天3~5杯是适宜的(标准咖啡杯容量为120毫升~140毫升),即每天摄入不超过210~400毫克咖啡因。
3. 咖啡不要喝得太晚
咖啡的饮用时间最好放在早餐或午餐后喝比较适宜,可促进代谢,帮助消化。如果下午或晚上再喝咖啡,可能会影响晚上睡眠质量。
图片关键词
健康时报王楠 摄
4. 胃不好不要空腹喝
胃不好的人群,尤其是慢性胃炎、胃食道反流等基础疾病的人群,建议最好别空腹喝咖啡。
5. 无饮用习惯别强求
每个人的身体情况和生活习惯不同,有人不喜欢喝咖啡,有人喝咖啡会出现尿频、心悸、肠胃不舒服等情况。如果没有喝咖啡的习惯,不必强求,也可以通过其他健康生活方式带来获益
本文综合自:①Manghi, P., Bhosle, A., Wang, K.et al.Coffee consumption is associated with intestinal Lawsonibacter asaccharolyticus abundance and prevalence across multiple cohorts. Nat Microbiol 9, 3120–3134 (2024). https://doi.org/10.1038/s41564-024-01858-9②Liu X, Li X, Ma J. Beverage consumption and facial skin aging: Evidence from Mendelian randomization analysis. J Cosmet Dermatol. 2024 May;23(5):1800-1807. doi: 10.1111/jocd.16153. Epub 2024 Jan 4. PMID: 38178620.③Fukushima Y, Takahashi Y, Hori Y, Kishimoto Y, Shiga K, Tanaka Y, Masunaga E, Tani M, Yokoyama M, Kondo K. Skin photoprotection and consumption of coffee and polyphenols in healthy middle-aged Japanese females. Int J Dermatol. 2015 Apr;54(4):410-8. doi: 10.1111/ijd.12399. Epub 2014 Jul 11. PMID: 25041334.④Light to moderate coffee consumption is associated with lower risk of death: a UK Biobank study. European Journal of Preventive Cardiology, 20 January 2022

Coffee, regarded by many as a "power tool" for refreshing the mind and preventing drowsiness, is even consumed by some people in the amount of 2-3 cups daily. Numerous studies have previously confirmed that drinking coffee indeed brings numerous health benefits.

Compared to those who never drink coffee, do these long-term coffee drinkers experience any physical changes? A recent study conducted by Harvard University found that coffee has a significant impact on the gut.

Photographed by Ren Xuan, Health Times

People who regularly drink coffee may experience significant changes in their gut microbiota!

In November 2024, researchers from Harvard University published a study involving tens of thousands of people in the journal Nature Microbiology, revealing that regular coffee consumption can alter gut microbiota. Compared to those who never drink coffee (consuming less than three cups per month), individuals who consume three cups of coffee daily have levels of beneficial bacteria (L. asaccharolyticus) in their intestines that are 4.5-8 times higher! ①

Research screenshot

This study is the largest one to date investigating the association between human gut microbiota and coffee consumption. The researchers categorized over 22,000 participants into three groups based on their coffee intake:

Group 1: Never drink coffee (less than 3 cups per month)

Group 2: Drinking a large amount of coffee (more than 3 cups per day)

Group 3: Moderate coffee consumption (between never drinking and heavy consumption)

Research has found a close correlation between coffee intake and human gut microbiota, with coffee exhibiting the strongest association among over 150 types of foods.

Compared to those who never drink coffee, the level of beneficial bacteria (L. asaccharolyticus) is 4.5-8 times higher in those who consume a large amount of coffee. In those who drink coffee moderately, the level of beneficial bacteria (L. asaccharolyticus) is 3.4-6.4 times higher, and this difference is consistent across all global populations.

Coffee beans, photographed by Cao Zihao from Health Times

People who drink coffee regularly and those who never drink coffee,

The gaps in three aspects are quite evident

1. There may be significant differences in intestinal flora

As pointed out in the aforementioned study, coffee significantly enhances the levels of L. asaccharolyticus, with the most pronounced difference observed between non-coffee drinkers and coffee drinkers

People who regularly drink coffee have higher levels of L. asaccharolyticus, a beneficial gut bacteria. L. asaccharolyticus is a beneficial gut bacteria that helps the gut produce butyric acid, which helps maintain the intestinal barrier function and helps prevent enteritis and bowel cancer.

2. Low risk of facial skin aging

In 2024, a study published by researchers from Peking Union Medical College in the Journal of Cosmetic Dermatology found that regular coffee drinkers can effectively reduce the risk of facial skin aging.

Research screenshot

The study comprehensively analyzed the causal relationship between the consumption of four types of beverages—tea, coffee, alcoholic beverages, and sugary drinks—and facial skin aging. The research revealed that among the four beverages, only coffee effectively reduces the risk of facial skin aging, with coffee intake decreasing the probability of facial aging by 15%. The remaining three beverages did not show a clear association with facial skin aging

In other words, people who regularly consume coffee have a lower risk of facial skin aging and appear younger. A similar study published in the International Journal of Dermatology in 2014 found that coffee intake can effectively protect human skin from photoaging and reduce pigmentation. Researchers speculate that the beauty benefits of coffee lie in its polyphenols, such as chlorogenic acid.③

3. Lower risk of cardiovascular disease

A study published in the European Journal of Preventive Cardiology in 2022 found that drinking 0.5 to 3 cups of coffee per day was associated with a 12% reduction in all-cause mortality and a 17% reduction in cardiovascular disease mortality. ④

Research indicates that coffee contains various bioactive components, such as caffeine and polyphenolic compounds. Caffeine can stimulate the central nervous system, enhance alertness and attention, and may also exert a certain stimulatory effect on metabolism.

Polyphenolic compounds, on the other hand, possess antioxidant and anti-inflammatory properties, which help protect body cells from damage caused by free radicals, thereby maintaining the normal function of various organs in the body, especially the cardiovascular system.

Health Times picture

Drink coffee healthily, remember these 5 points

1. Don't drink coffee too hot

Whether it's coffee or other hot beverages, avoid drinking them too hot. In 2016, the International Agency for Research on Cancer (IARC) announced the carcinogenicity assessment results for overheated beverages such as coffee. Drinks with temperatures exceeding 65°C were classified as Group 2A carcinogens. This means that while the evidence for human carcinogenicity is limited, it is likely to cause cancer.

2. It's best not to drink more than 5 cups per day

It is recommended not to drink more than 5 cups of coffee per day. According to the "Scientific Consensus on Coffee and Health" jointly issued by the Institute for Nutrition and Health of the Chinese Center for Disease Control and Prevention in 2018, it is advisable for healthy adults to drink 3 to 5 cups per day (with a standard coffee cup capacity of 120 ml to 140 ml), which means consuming no more than 210 to 400 mg of caffeine per day.

3. Don't drink coffee too late

It is more appropriate to drink coffee after breakfast or lunch, as it can promote metabolism and aid digestion. Drinking coffee in the afternoon or evening may affect the quality of sleep at night.

Photographed by Wang Nan, Health Times

4. If you have a weak stomach, avoid drinking on an empty stomach

People with poor stomach health, especially those with underlying conditions such as chronic gastritis and gastroesophageal reflux, are advised not to drink coffee on an empty stomach.

5. Don't force drinking habits if you don't have them

Everyone has different physical conditions and lifestyle habits. Some people don't like to drink coffee, while others may experience urinary frequency, palpitations, and gastrointestinal discomfort after drinking coffee. If you don't have a habit of drinking coffee, there's no need to force yourself. You can still benefit from other healthy lifestyles.

This article is synthesized from:

①Manghi, P., Bhosle, A., Wang, K.et al.Coffee consumption is associated with intestinal Lawsonibacter asaccharolyticus abundance and prevalence across multiple cohorts. Nat Microbiol 9, 3120–3134 (2024). https://doi.org/10.1038/s41564-024-01858-9

②Liu X, Li X, Ma J. Beverage consumption and facial skin aging: Evidence from Mendelian randomization analysis. J Cosmet Dermatol. 2024 May;23(5):1800-1807. doi: 10.1111/jocd.16153. Epub 2024 Jan 4. PMID: 38178620.

③Fukushima Y, Takahashi Y, Hori Y, Kishimoto Y, Shiga K, Tanaka Y, Masunaga E, Tani M, Yokoyama M, Kondo K. Skin photoprotection and consumption of coffee and polyphenols in healthy middle-aged Japanese females. Int J Dermatol. 2015 Apr;54(4):410-8. doi: 10.1111/ijd.12399. Epub 2014 Jul 11. PMID: 25041334.

④Light to moderate coffee consumption is associated with lower risk of death: a UK Biobank study. European Journal of Preventive Cardiology, 20 January 2022


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